A recent study suggests that executive functions can be rapidly up- or down-regulated by modulating theta phase coupling of distant frontal cortical areas and can contribute to the development of tools for potentially normalizing executive dysfunction in patient populations.
About 75 percent of people with MS (Multiple Sclerosis) report fatigue among their most disabling disease symptoms.
Medications, such as those that treat narcolepsy, behavior-based therapies and even exercise programs are often prescribed but benefits have been found to be unreliable.
When compared to patients who were enrolled in a placebo arm of a recent study those that received transcranial direct current stimulation (tDCS) were found to have about a six-point drop on a 32-point scale measuring fatigue severity, according to the findings recently published online in the Multiple Sclerosis Journal.
The exact mechanism behind tDCS is unclear and requires more research. It is thought to change the brain's cortical excitability by making it easier for neurons to fire, thereby improving connections and expediting learning that takes place during rehabilitation.
In a recent trial, a vegetative-state patient responds to Vagal Nerve Stimulation (VNS) in an experimental therapy.
However, article suggests that VNS may not work as effectively in patients with different patterns of brain damage.
Perhaps a fully-programmable electrical pulse generator platform is ideal for this application, since it is not practical to develop custom pulse generators for every patient using an ASIC-based platform.
New treatment options are being studied and proposed but much work is required to understand how these technologies are best matched with specific patients and pain syndromes.
A recent article delves into the details of this topic. The article concludes with a statement that "the field will undoubtedly continue to grow and force reconsideration of current treatment paradigms.".
This implies that new research on new paradigms require new devices. Flexible, programmable, indication-agnostic devices can play a key role in accelerating medical research, given the fact that developing a new purpose-built device requires a dedicated development team and heavy investment in time, and money.
A programmable device can enable new research overnight.
A new pilot trial is aiming to determine the feasibility, safety and perceived patient response to a combined transcranial direct current stimulation (tDCS) and sensorimotor retraining intervention in chronic lower back pain and provide data to support a sample size calculation for a fully powered trial should trends of effectiveness be present.
This is a good article on combating opioid misuse.
Now read this: Pharmacies are dispensing 245M opioid prescriptions every year!
This begs a question: Since there are lower cost, better outcome, non-addicting, totally reversible alternatives with no or little side effects such as medical devices, why are we considering opioids for therapy at all?
One may say: Medical devices are expensive. No!!! not any more. There are very low cost, fully programmable platforms one can adopt for any indication literally overnight. So, why is this push for opioids?
We are losing loved ones on opioids every day, isn't it time to say NO to opioids?
Researchers at King’s College London in the UK have recently looked at tDCS (transcranial direct current stimulation) as a potential approach to improve cognition in patients with schizophrenia. The results are promising.
A new study is recruiting participants. The study aims to provide non-Invasive therapies for people with spinal cord injury. Click here to read more.
Obesity and related illnesses claim more than 400,000 lives and account for $150 billion in annual spending on health care in the U.S. alone.
Currently, the only effective, long-term therapy is surgery, such as gastric bypass or gastric banding, which can carry serious risks.
The procedure to implant a gastric electrical stimulators however, are less invasive and offer a simple solution: These can be used to slow the pace at which food empties from the stomach, thereby creating a sensation of fullness and reducing the amount of food consumed.
Obesity is a major worldwide health problem. In the United States, about one-third of the population is obese and more than 15 million patients face such serious health risks from morbid obesity that they need treatment.
Electrical neurostimulation may be the solution many patients have been awaiting globally as a low risk and reversible alternative to dangerous surgical options.
Nature uses fractals everywhere. For instance, bronchial trees transfer oxygen to the bloodstream, trees absorb sunlight, and coastlines to disperse wave energy very efficiently by their natural fractal geometries. Learning from the nature, novel fractal electrode designs' large surface areas increase their capacity to hold electrical charge, which in turn generate larger electric fields than their non-fractal counterparts.
According to a recent research, fractal electrode designs outperform Euclidean geometries and may improve patient outcomes in neuronal stimulation.
Lone Star NeuroMODULATION
LSN is targeting unmet clinical needs by creating disruptive device platforms that offer promising solutions for lowering costs, realizing higher returns and effectively addressing more therapeutic indications if adopted for medical applications.